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TCS JNK 5a is a highly selective inhibitor of JNK2 and JNK3 (pIC50 values are 6.7, 6.5, <5.0 and <4.8 for JNK3, JNK2, JNK1 and p38?? respectively).
| In vitro | DMSO | 19 mg/mL (57.15 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.08 mL | 150.41 mL | 300.82 mL |
| 0.5 mM | 6.02 mL | 30.08 mL | 60.16 mL |
| 1 mM | 3.01 mL | 15.04 mL | 30.08 mL |
| 5 mM | 0.6 mL | 3.01 mL | 6.02 mL |
*The above data is based on the productmolecular weight 332.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11969 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 312917-14-9 |
| Formula | C20H16N2OS |
| M. Wt | 332.42 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | JNK Inhibitor IX |
| SMILES | C1CCC2=C(C1)C(=C(S2)NC(=O)C3=CC=CC4=CC=CC=C43)C#N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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