TD-0212

Catalog No.: A13715

neprilysin (NEP) inhibitor

TD-0212

TD-0212 Chemical Structure

CAS NO. 1073549-10-6

TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP.

Availability: In stock

Package Price Qty
1 mg
$360.00
5 mg
$1,080.00
10 mg
$1,840.00
50 mg
$5,520.00
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Biological Activity

TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.95 mL 94.76 mL 189.52 mL
0.5 mM 3.79 mL 18.95 mL 37.9 mL
1 mM 1.9 mL 9.48 mL 18.95 mL
5 mM 0.38 mL 1.9 mL 3.79 mL

*The above data is based on the productmolecular weight 527.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13715
Actions Inhibitor
M. Wt 527.65
Formula C28H34FN3O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1073549-10-6
Synonyms TD0212, TD-0212
SMILES OC(C1=CC=CC=C1C2=CC=C(CN3C(CNC([[email protected]](CC(C)C)S)=O)=C(CC)N=C3OCC)C(F)=C2)=O

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