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$0.00 Biological Activity
TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.95 mL | 94.76 mL | 189.52 mL |
| 0.5 mM | 3.79 mL | 18.95 mL | 37.9 mL |
| 1 mM | 1.9 mL | 9.48 mL | 18.95 mL |
| 5 mM | 0.38 mL | 1.9 mL | 3.79 mL |
*The above data is based on the productmolecular weight 527.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13715 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1073549-10-6 |
| Formula | C28H34FN3O4S |
| M. Wt | 527.65 |
| Purity | >98% |
| Synonyms | TD0212, TD-0212 |
| SMILES | OC(C1=CC=CC=C1C2=CC=C(CN3C(CNC([[email protected]](CC(C)C)S)=O)=C(CC)N=C3OCC)C(F)=C2)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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