Neprilysin

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  1. Racecadotril is a potent enkephalinase inhibitor which exhibits selective antisecretory activity.
  2. neprilysin inhibitor

    AHU-377 is an inhibitor of neprilysin with IC50 value of 5nM.
  3. angiotensin receptor-neprilysin inhibitor

    LCZ696 is an orally bioavailable, dual-acting angiotensin receptor-neprilysin inhibitor (ARNi) for hypertension and heart failure.
  4. NEP inhibitor

    Candoxatril is a neutral endopeptidase (NEP) inhibitor.
  5. NEP inhibitor

    Sacubitrilat is an active neprilysin (NEP) inhibitor.
  6. NEP inhibitor

    Sch-42495 racemate is the racemate of Sch-42495. Sch-42495 is a novel neutral metalloendopeptidase (NEP) inhibitor. Sch-42495 is the orally active ethylester prodrug of SCH 42354.
  7. Opiorphin, an opioid peptide, is a potent enkephalin-inactivating zinc ectopeptidases in human inhibitor. Opiorphin inhibits two enkephalin-catabolizing ectoenzymes, human neutral ecto-endopeptidase, hNEP (EC 3.4.24.11) with an IC50 value of 11 μM, and human ecto-aminopeptidase, hAP-N (EC 3.4.11.2). Opiorphin displays potent analgesic activity by activating endogenous opioid-dependent transmission.

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