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Tenalisib, also known as RP6530, is a potent and selective dual PI3Kδ/γ inhibitor that inhibited growth of B-cell lymphoma cell lines with a concomitant reduction in the downstream biomarker, pAKT.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.07 mL | 120.36 mL | 240.71 mL |
| 0.5 mM | 4.81 mL | 24.07 mL | 48.14 mL |
| 1 mM | 2.41 mL | 12.04 mL | 24.07 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.81 mL |
*The above data is based on the productmolecular weight 415.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16799 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 415.43 |
| Formula | C23H18FN5O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1639417-53-0 |
| Synonyms | RP-6530, RP 6530 |
| SMILES | O=C1C(C2=CC=CC(F)=C2)=C([[email protected]@H](NC3=C4NC=NC4=NC=N3)CC)OC5=C1C=CC=C5 |
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