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Tenalisib, also known as RP6530, is a potent and selective dual PI3Kδ/γ inhibitor that inhibited growth of B-cell lymphoma cell lines with a concomitant reduction in the downstream biomarker, pAKT.
| In vitro | DMSO | 74 mg/mL (178.13 mM) | |
| Water | Insoluble | ||
| Ethanol | 74 mg/mL (178.13 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.07 mL | 120.36 mL | 240.71 mL |
| 0.5 mM | 4.81 mL | 24.07 mL | 48.14 mL |
| 1 mM | 2.41 mL | 12.04 mL | 24.07 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.81 mL |
*The above data is based on the productmolecular weight 415.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16799 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1639417-53-0 |
| Formula | C23H18FN5O2 |
| M. Wt | 415.43 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | RP-6530, RP 6530 |
| SMILES | O=C1C(C2=CC=CC(F)=C2)=C([[email protected]@H](NC3=C4NC=NC4=NC=N3)CC)OC5=C1C=CC=C5 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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