Tenovin-6

Catalog No.: A12305

p53 activator

Tenovin-6 Chemical Structure

CAS NO. 1011557-82-6

Tenovin-6 is a analog of tenovin-1. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 in vitro with IC50 values of 21, 10, and 67 uM, respectively.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $70.00

Special Price $56.00

10 mg

Regular Price: $90.00

Special Price $72.00

25 mg

Regular Price: $160.00

Special Price $128.00

10mM * 1mL in DMSO
$50.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Tenovin-6 is a analog of tenovin-1. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 in vitro with IC50 values of 21, 10, and 67 uM, respectively.
Targets
p53 SIRT2 SIRT1 SIRT3
N/A10 μM21 μM67 μM
In vitro DMSO 98 mg/mL (215.55 mM)
Water 98 mg/mL heating (215.55 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22 mL 109.99 mL 219.97 mL
0.5 mM 4.4 mL 22 mL 43.99 mL
1 mM 2.2 mL 11 mL 22 mL
5 mM 0.44 mL 2.2 mL 4.4 mL

*The above data is based on the productmolecular weight 454.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12305
Actions Activator
M. Wt 454.6
Formula C25H34N4O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1011557-82-6
Synonyms Tenovin6, Tenovin 6
SMILES CC(C)(C)C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=C(C=C2)NC(=O)CCCCN(C)C

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