tert-Butyl (2-(chlorosulfonyl)ethyl)carbamate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound effectively enables the conjugation of targeting ligands to E3 ligases, thereby promoting targeted protein degradation. Its utility in chemical biology research enhances the potential for therapeutic applications through modulation of protein levels in cells.
tert-Butyl (2-(chlorosulfonyl)ethyl)carbamate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound effectively enables the conjugation of targeting ligands to E3 ligases, thereby promoting targeted protein degradation. Its utility in chemical biology research enhances the potential for therapeutic applications through modulation of protein levels in cells.
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