Tert-butyl 3-(((benzyloxy)carbonyl)amino)propanoate

Catalog No.: A84323
PROTAC Linker
Tert-butyl 3-(((benzyloxy)carbonyl)amino)propanoate is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). Its structural features enhance the efficacy of target protein degradation, making it a valuable tool for chemical biology research. This compound is instrumental in the design and synthesis of novel therapeutic agents aimed at modulating protein levels in various biological contexts.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTert-butyl 3-(((benzyloxy)carbonyl)amino)propanoate is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). Its structural features enhance the efficacy of target protein degradation, making it a valuable tool for chemical biology research. This compound is instrumental in the design and synthesis of novel therapeutic agents aimed at modulating protein levels in various biological contexts.
Product Information
Catalog NumA84323
FormulaC15H21NO4
Molecular Weight279.34
CAS Number18605-26-0
SMILESO=C(OCC=1C=CC=CC1)NCCC(=O)OC(C)(C)C
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