tert-Butyl 4-(3-hydroxyprop-1-yn-1-yl)piperidine-1-carboxylate

Catalog No.: A84067
PROTAC Linker
tert-Butyl 4-(3-hydroxyprop-1-yn-1-yl)piperidine-1-carboxylate serves as an effective PROTAC linker. Its primary function is to facilitate the development of proteolysis-targeting chimeras (PROTACs), which enhance targeted protein degradation pathways. This compound is essential for studies aimed at optimizing PROTAC design and investigating protein homeostasis in cellular models.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiontert-Butyl 4-(3-hydroxyprop-1-yn-1-yl)piperidine-1-carboxylate serves as an effective PROTAC linker. Its primary function is to facilitate the development of proteolysis-targeting chimeras (PROTACs), which enhance targeted protein degradation pathways. This compound is essential for studies aimed at optimizing PROTAC design and investigating protein homeostasis in cellular models.
Product Information
Catalog NumA84067
FormulaC13H21NO3
Molecular Weight239.32
CAS Number403802-41-5
SMILESO=C(OC(C)(C)C)N1CCC(C#CCO)CC1
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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