tert-Butyl (azetidin-3-ylmethyl)(methyl)carbamate

Catalog No.: A84281
PROTAC Linker
tert-Butyl (azetidin-3-ylmethyl)(methyl)carbamate is a PROTAC linker designed to facilitate the development of protein degradation therapeutics through targeted protein degradation mechanisms. This compound plays a crucial role in the synthesis of PROTACs, enabling effective ubiquitination and subsequent proteasomal degradation of specific target proteins. Its application in chemical biology and pharmacology holds promise for advancing research in targeted therapies and protein regulation studies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiontert-Butyl (azetidin-3-ylmethyl)(methyl)carbamate is a PROTAC linker designed to facilitate the development of protein degradation therapeutics through targeted protein degradation mechanisms. This compound plays a crucial role in the synthesis of PROTACs, enabling effective ubiquitination and subsequent proteasomal degradation of specific target proteins. Its application in chemical biology and pharmacology holds promise for advancing research in targeted therapies and protein regulation studies.
Product Information
Catalog NumA84281
FormulaC10H20N2O2
Molecular Weight200.28
CAS Number1053655-53-0
SMILESO=C(OC(C)(C)C)N(C)CC1CNC1
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