tert-Butyl cis-4-(2-aminoethyl)cyclohexylcarbamate

Catalog No.: A84419
PROTAC Linker
tert-Butyl cis-4-(2-aminoethyl)cyclohexylcarbamate is a PROTAC linker utilized in the synthesis of PROTAC (Proteolysis-Targeting Chimeras) molecules. This compound enhances the development of targeted protein degradation systems, facilitating the selective removal of specific proteins from cells. It serves as a crucial component in research aimed at addressing various diseases by enabling the modulation of protein levels through controlled proteolysis.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiontert-Butyl cis-4-(2-aminoethyl)cyclohexylcarbamate is a PROTAC linker utilized in the synthesis of PROTAC (Proteolysis-Targeting Chimeras) molecules. This compound enhances the development of targeted protein degradation systems, facilitating the selective removal of specific proteins from cells. It serves as a crucial component in research aimed at addressing various diseases by enabling the modulation of protein levels through controlled proteolysis.
Product Information
Catalog NumA84419
FormulaC13H26N2O2
Molecular Weight242.36
CAS Number509143-12-8
SMILESN(C(OC(C)(C)C)=O)[C@H]1CC[C@@H](CCN)CC1
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