Tert-butyl(hex-5-yn-1-yloxy)dimethylsilane

Catalog No.: A84166
PROTAC Linker
Tert-butyl(hex-5-yn-1-yloxy)dimethylsilane serves as an effective PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). Its structure enables the efficient conjugation of target proteins and E3 ligases, thereby promoting targeted protein degradation. This compound is valuable in the design of novel therapeutic agents for drug discovery and development in various biological studies.
Grouped product items
Size Price Stock Qty
25mg
$45.00
In stock
50mg
$75.00
In stock
100mg
$120.00
In stock
250mg
$230.00
In stock
500mg
$365.00
In stock
1g
$585.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTert-butyl(hex-5-yn-1-yloxy)dimethylsilane serves as an effective PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). Its structure enables the efficient conjugation of target proteins and E3 ligases, thereby promoting targeted protein degradation. This compound is valuable in the design of novel therapeutic agents for drug discovery and development in various biological studies.
Product Information
Catalog NumA84166
FormulaC12H24OSi
Molecular Weight212.41
CAS Number73448-13-2
SMILESC#CCCCCO[Si](C)(C)C(C)(C)C
Useful Calculator

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