Tetraethyl butane-1,4-diylbis(phosphonate)

Catalog No.: A83188
PROTAC Linkers
Tetraethyl butane-1,4-diylbis(phosphonate) serves as an alkyl chain-based linker for PROTAC (Proteolysis Targeting Chimeras) synthesis, facilitating targeted protein degradation. This reagent's structural features enhance the specificity and efficacy of PROTACs, making it valuable in the study of protein turnover and cellular regulation mechanisms. Its applications include developing novel therapeutics and exploring the dynamics of protein interactions within various biological contexts.
Grouped product items
Size Price Stock Qty
100mg
$95.00
In stock
250mg
$195.00
In stock
1g
$490.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTetraethyl butane-1,4-diylbis(phosphonate) serves as an alkyl chain-based linker for PROTAC (Proteolysis Targeting Chimeras) synthesis, facilitating targeted protein degradation. This reagent's structural features enhance the specificity and efficacy of PROTACs, making it valuable in the study of protein turnover and cellular regulation mechanisms. Its applications include developing novel therapeutics and exploring the dynamics of protein interactions within various biological contexts.
Product Information
Catalog NumA83188
FormulaC12H28O6P2
Molecular Weight330.29
CAS Number7203-67-0
SMILESO=P(OCC)(OCC)CCCCP(OCC)(OCC)=O
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