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Tetraethyl decane-1,10-diylbis(phosphonate)

PROTAC Linkers

Tetraethyl decane-1,10-diylbis(phosphonate) is a phosphonate-based linker designed for use in the development of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the targeted degradation of specific proteins by linking E3 ligases with the protein of interest, enhancing cellular activity through the modulation of protein turnover. Its unique structure allows for effective construction of PROTACs, making it a valuable tool in drug discovery and research focused on targeted protein degradation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	5943-62-4
Applications	PROTAC Linkers
Formula	C₁₈H₄₀O₆P₂
Molecular Weight	414.45
SMILES	O=P(OCC)(OCC)CCCCCCCCCCP(OCC)(OCC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.