Tetraethyl heptane-1,7-diylbis(phosphonate)

Catalog No.: A83210
PROTAC Linkers
Tetraethyl heptane-1,7-diylbis(phosphonate) is a versatile linker utilized in the development of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound features an alkyl chain structure that facilitates the construction of bifunctional PROTACs, allowing for targeted protein degradation. It is instrumental in studies of targeted therapy and has applications in various drug discovery research efforts aimed at modulating protein levels within cellular systems.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTetraethyl heptane-1,7-diylbis(phosphonate) is a versatile linker utilized in the development of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound features an alkyl chain structure that facilitates the construction of bifunctional PROTACs, allowing for targeted protein degradation. It is instrumental in studies of targeted therapy and has applications in various drug discovery research efforts aimed at modulating protein levels within cellular systems.
Product Information
Catalog NumA83210
FormulaC15H34O6P2
Molecular Weight372.37
CAS Number5943-17-9
SMILESO=P(CCCCCCCP(OCC)(OCC)=O)(OCC)OCC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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