TG101209

Catalog No.: A11180

JAK2 inhibitor

TG101209

TG101209 Chemical Structure

CAS NO. 936091-14-4

TG101209, a novel JAK2 inhibitor, has significant in vitro activity in multiple myeloma and displays preferential cytotoxicity for CD45+ myeloma cells.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$120.00
50 mg
$270.00
100 mg
$485.00
10mM * 1mL in DMSO
$100.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TG101209, a novel JAK2 inhibitor, has significant in vitro activity in multiple myeloma and displays preferential cytotoxicity for CD45+ myeloma cells.

Targets
JAK2 (Cell-free assay) RET (Cell-free assay) FLT3 (Cell-free assay) JAK3 (Cell-free assay)
6 nM17 nM25 nM169 nM
In vitro (25°C) DMSO 94 mg/mL (184.42 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 11 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.62 mL 98.1 mL 196.21 mL
0.5 mM 3.92 mL 19.62 mL 39.24 mL
1 mM 1.96 mL 9.81 mL 19.62 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 509.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11180
Actions Inhibitor
CAS No. 936091-14-4
Formula C26H35N7O2S
M. Wt 509.67
Purity >98%
Synonyms TG-101209
SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3N=C(NC4=CC(=CC=C4)S(=O)(=O)NC(C)(C)C)C(C)=CN=3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy TG101209 | TG101209 Supplier | purchase | cost | manufacturer | order | distributor | buy 936091-14-4| 936091-14-4 Supplier | purchase 936091-14-4 | 936091-14-4 cost | 936091-14-4 manufacturer | order 936091-14-4 | 936091-14-4 distributor
Rewards