Anirudh Sattiraju, .et al. , bioRxiv, 2022, March 04
Biological Activity
Description
TH-302 is a selectively targeting hypoxic regions of solid tumors hypoxia-activated prodrug.
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A11144
Formula
C9H16Br2N5O4P
Molecular Weight
449
CAS Number
918633-87-1
SMILES
CN1C(=CN=C1[N+](=O)[O-])COP(=O)(NCCBr)NCCBr
Synonyms
TH302
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
80 mg/mL (178.15 mM)
Water
Warmed: 9 mg/mL (20.03 mM)
Ethanol
80 mg/mL (178.15 mM)
In vivo
30% propylene glycol, 5% Tween 80, 65% D5W
28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: