TH-302 (Evofosfamide)

TH-302 is a selectively targeting hypoxic regions of solid tumors hypoxia-activated prodrug.
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TH-302 5mg
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TH-302 100mg
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Adooq Products cited in reputable paper
Adooq's TH-302 (Evofosfamide) has been cited by 2 publications
  • Anirudh Sattiraju, .et al. , Immunity, 2023, Aug 8;56(8):1825-1843 PMID: 37451265
  • Anirudh Sattiraju, .et al. , bioRxiv, 2022, March 04
  • Biological Activity
    Discription TH-302 is a selectively targeting hypoxic regions of solid tumors hypoxia-activated prodrug.
    Product Information
    Catalog Num A11144
    Formula C9H16Br2N5O4P
    Molecular Weight 449
    CAS Number 918633-87-1
    SMILES CN1C(=CN=C1[N+](=O)[O-])COP(=O)(NCCBr)NCCBr
    Synonyms TH302

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 80 mg/mL (178.15 mM)
    Water Warmed: 9 mg/mL (20.03 mM)
    Ethanol 80 mg/mL (178.15 mM)
    In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.27 mL 111.36 mL 222.72 mL
    0.5 mM 4.45 mL 22.27 mL 44.54 mL
    1 mM 2.23 mL 11.14 mL 22.27 mL
    5 mM 0.45 mL 2.23 mL 4.45 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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