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TH588 hydrochloride is first-in-class nudix hydrolase family inhibitor that potently and selectively engage and inhibit the MTH1 (IC50= 5 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.15 mL | 150.77 mL | 301.54 mL |
| 0.5 mM | 6.03 mL | 30.15 mL | 60.31 mL |
| 1 mM | 3.02 mL | 15.08 mL | 30.15 mL |
| 5 mM | 0.6 mL | 3.02 mL | 6.03 mL |
*The above data is based on the productmolecular weight 331.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21653 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1640282-30-9 |
| Formula | C13H13Cl3N4 |
| M. Wt | 331.63 |
| Purity | >98% |
| Synonyms | TH 588, TH-588 |
| SMILES | NC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC3CC3)=N1.[H]Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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