Thalidomide 5-pyrrolidine-CHO

Catalog No.: A80305
E3 Ligase Ligand-Linker Conjugates
Thalidomide 5-pyrrolidine-CHO is a conjugate designed for E3 ubiquitin ligase ligand-linker applications. This compound facilitates protein degradation by linking to E3 ligases, enabling targeted protein modulation. It serves as a valuable tool in the development and synthesis of novel bivalent degraders, such as NRX-0492. Researchers can utilize this compound for studies related to targeted therapeutics and protein homeostasis regulation.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide 5-pyrrolidine-CHO is a conjugate designed for E3 ubiquitin ligase ligand-linker applications. This compound facilitates protein degradation by linking to E3 ligases, enabling targeted protein modulation. It serves as a valuable tool in the development and synthesis of novel bivalent degraders, such as NRX-0492. Researchers can utilize this compound for studies related to targeted therapeutics and protein homeostasis regulation.
Product Information
Catalog NumA80305
FormulaC18H17N3O5
Molecular Weight355.34
CAS Number2416132-74-4
SMILESO=C[C@H]1CN(C2=CC3=C(C(N(C(CC4)C(NC4=O)=O)C3=O)=O)C=C2)CC1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2