Thalidomide-O-amido-C8-NH2 hydrochloride functions as an E3 ligase ligand-linker conjugate, incorporating the Thalidomide-derived cereblon ligand along with a suitable linker. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs), enabling targeted protein degradation in research applications. Its structural features facilitate selective binding to E3 ligases, making it a valuable tool in drug discovery and cellular function studies.
Thalidomide-O-amido-C8-NH2 hydrochloride functions as an E3 ligase ligand-linker conjugate, incorporating the Thalidomide-derived cereblon ligand along with a suitable linker. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs), enabling targeted protein degradation in research applications. Its structural features facilitate selective binding to E3 ligases, making it a valuable tool in drug discovery and cellular function studies.
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