Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate targeting cereblon, a key component in the ubiquitin-proteasome pathway. This compound is designed to facilitate targeted protein degradation through PROTAC technology, enabling researchers to manipulate cellular protein levels with high specificity. Its unique linker structure enhances the conjugate’s stability and efficacy in various biological applications, making it a valuable tool for studying protein regulation and therapeutic interventions.
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate targeting cereblon, a key component in the ubiquitin-proteasome pathway. This compound is designed to facilitate targeted protein degradation through PROTAC technology, enabling researchers to manipulate cellular protein levels with high specificity. Its unique linker structure enhances the conjugate’s stability and efficacy in various biological applications, making it a valuable tool for studying protein regulation and therapeutic interventions.
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