Thalidomide-O-amido-PEG4-propargyl is a PEG-based PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound features an alkyne functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) for efficient conjugation with azide-containing molecules. Its unique properties enable precise modulation of target protein degradation, supporting research in targeted protein modulation and therapeutic applications.
Thalidomide-O-amido-PEG4-propargyl is a PEG-based PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound features an alkyne functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) for efficient conjugation with azide-containing molecules. Its unique properties enable precise modulation of target protein degradation, supporting research in targeted protein modulation and therapeutic applications.
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