Thalidomide-S-C6-acid is a synthetic E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon ligand with a C6 linker. This compound facilitates the development of PROTACs, specifically designed for targeted protein degradation applications, including the synthesis of the PROTAC Cas9 Degrader-1. Its ability to engage with E3 ligases makes it a valuable tool in biochemistry and molecular biology research focused on therapeutic interventions through targeted protein modulation.
Thalidomide-S-C6-acid is a synthetic E3 ligase ligand-linker conjugate that combines a thalidomide-derived cereblon ligand with a C6 linker. This compound facilitates the development of PROTACs, specifically designed for targeted protein degradation applications, including the synthesis of the PROTAC Cas9 Degrader-1. Its ability to engage with E3 ligases makes it a valuable tool in biochemistry and molecular biology research focused on therapeutic interventions through targeted protein modulation.
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