Thiol-PEG5-acid is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This linker facilitates the conjugation of targeting moieties to E3 ligase binders, enabling the modulation of protein degradation pathways. Its hydrophilic nature enhances the solubility and bioavailability of PROTACs, making it a valuable tool in drug discovery and development research.
Thiol-PEG5-acid is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This linker facilitates the conjugation of targeting moieties to E3 ligase binders, enabling the modulation of protein degradation pathways. Its hydrophilic nature enhances the solubility and bioavailability of PROTACs, making it a valuable tool in drug discovery and development research.
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