THP-PEG4-Pyrrolidine(N-Me)-CH2OH

Catalog No.: A82697
PROTAC Linker
THP-PEG4-Pyrrolidine(N-Me)-CH2OH is a polyethylene glycol (PEG)-based linker designed for use in PROTAC technology. This linker facilitates the synthesis of novel PROTAC compounds, notably the K-Ras Degrader-1, by promoting the degradation of specific target proteins via the ubiquitin-proteasome pathway. It is particularly useful in studies focused on targeted protein degradation for therapeutic applications.
Grouped product items
Size Price Stock Qty
2mg
$30.00
In stock
25mg
$135.00
In stock
50mg
$210.00
In stock
100mg
$330.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTHP-PEG4-Pyrrolidine(N-Me)-CH2OH is a polyethylene glycol (PEG)-based linker designed for use in PROTAC technology. This linker facilitates the synthesis of novel PROTAC compounds, notably the K-Ras Degrader-1, by promoting the degradation of specific target proteins via the ubiquitin-proteasome pathway. It is particularly useful in studies focused on targeted protein degradation for therapeutic applications.
Product Information
Catalog NumA82697
FormulaC19H37NO7
Molecular Weight391.50
CAS Number2378261-81-3
SMILESOC[C@@H]1C[C@H](CN1C)OCCOCCOCCOCCOC2CCCCO2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2