TIC10

Catalog No.: A15903

Akt Inhibitor‎

TIC10 Chemical Structure

CAS NO. 1616632-77-9

TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.

Availability: In stock

Package Price Qty
10 mg
$65.00
25 mg
$100.00
50 mg
$130.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
Targets
Akt ERK
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.87 mL 129.37 mL 258.74 mL
0.5 mM 5.17 mL 25.87 mL 51.75 mL
1 mM 2.59 mL 12.94 mL 25.87 mL
5 mM 0.52 mL 2.59 mL 5.17 mL

*The above data is based on the productmolecular weight 386.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15903
Actions Inhibitor
M. Wt 386.49
Formula C24H26N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1616632-77-9
Synonyms ONC-201
SMILES CC1=CC=CC=C1CN(C2=NCCN32)C(C(C4)=C3CCN4CC5=CC=CC=C5)=O

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