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Tigecycline

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Catalog No. A10933

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Tigecycline 10mg A10933-10

Regular Price: $90.00

Special Price: $81.00

Tigecycline 25mg A10933-25

Regular Price: $120.00

Special Price: $108.00

Tigecycline 50mg A10933-50

Regular Price: $160.00

Special Price: $144.00

Tigecycline 100mg A10933-100

Regular Price: $300.00

Special Price: $270.00

Tigecycline 10mM * 1mL in DMSO A10933-10mM-D

Regular Price: $98.00

Special Price: $88.20

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation.

Tigecycline

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Publications citing Adooq Products
Tigecycline Citations (3)
  • Sato T, .et al. Tigecycline Susceptibility of Klebsiella pneumoniae Complex and Escherichia coli Isolates from Companion Animals: The Prevalence of Tigecycline-Nonsusceptible K. pneumoniae Complex, Including Internationally Expanding Human Pathogenic Lineages, Microb Drug Resist, 2018, Jul/Aug;24(6):860-867 PMID: 29232167
  • Dinah B. Aziz, .et al. Teicoplanin - Tigecycline Combination Shows Synergy Against Mycobacterium abscessus, Front Microbiol, 2018, May 11 PMID: 29867841
  • Toyotaka Sato, .et al. Tigecycline Nonsusceptibility Occurs Exclusively in Fluoroquinolone-Resistant Escherichia coli Clinical Isolates, Including the Major Multidrug-Resistant Lineages O25b:H4-ST131-H30R and O1-ST648, Antimicrob Agents Chemother, 2017, Feb; 61(2): e01654-16 PMID: 27855067

Chemical Information

Catalog Num A10933
Actions No
M. Wt 585.7
Formula C29H39N5O8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 220620-09-7
Synonyms Tygacil, GAR-936, WAY-GAR-936, TBG-MINO
SMILES CC(C)(C)NCC(=O)NC1=C(C2=C(C[[email protected]]3C[[email protected]]4[[email protected]@H](C(=O)C(=C([[email protected]]4(C(=O)C3=C2O)O)O)C(=O)N)N(C)C)C(=C1)N(C)C)O

Biological Activity

Description
Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation.

Solubility

Solubility (25°C) * In vitro DMSO 100 mg/mL (170.75 mM)
Water 100 mg/mL (170.75 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.07 mL 85.37 mL 170.74mL
0.5 mM 3.41 mL 17.07 mL 34.15 mL
1 mM 1.71 mL 8.54 mL 17.07 mL
5 mM 0.34 mL 1.71 mL 3.41 mL

*The above data is based on the productmolecular weight 585.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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