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Tiplaxtinin is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 μM.
Targets
| PAI-1 | ||||
| 2.7 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.76 mL | 113.8 mL | 227.59 mL |
| 0.5 mM | 4.55 mL | 22.76 mL | 45.52 mL |
| 1 mM | 2.28 mL | 11.38 mL | 22.76 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.55 mL |
*The above data is based on the productmolecular weight 439.3833. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14190 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 439.3833 |
| Formula | C24H16F3NO4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 393105-53-8 |
| Synonyms | PAI-039 |
| SMILES | C1=CC=C(C=C1)CN2C=C(C3=C2C=CC(=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O |
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