Catalog No.
Product Name
Application
Product Information
Product Citation
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PAI-1 inhbitor
Tiplaxtinin is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 μM.- Saijo A, .et al. , Cancer Lett, 2018, May 1;421:17-27 PMID: 29448000
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plasminogen activator inhibitor
TM5275 sodium is a plasminogen activator inhibitor (PAI-1) with an IC50 of 6.95 μM.- Yapeng Hou, .et al. , Am J Physiol Lung Cell Mol Physiol, 2022, 1;323(5):L569-L577 PMID: 36193902
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uPA inhibitor
UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin). -
PAI-1 inhibitor
Angstrom6 (A6 Peptide) is an 8 amino-acid peptide derived from single-chain urokinase plasminogen activator (scuPA) and interferes with the uPA/uPAR cascade and abrogates downstream effects. Angstrom6 binds to CD44 resulting in the inhibition of migration, invasion, and metastasis of tumor cells, and the modulation of CD44-mediated cell signaling.