TM5441

Catalog No.: A19369

PAI-1 inhibitor

TM5441

TM5441 Chemical Structure

CAS NO. 1190221-43-2

TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines.

Availability: In stock

Package Price Qty
2 mg
$80.00
5 mg
$130.00
10 mg
$200.00
50 mg
$720.00
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Biological Activity

TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.32 mL 116.6 mL 233.2 mL
0.5 mM 4.66 mL 23.32 mL 46.64 mL
1 mM 2.33 mL 11.66 mL 23.32 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 428.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19369
Actions Inhibitor
M. Wt 428.82
Formula C21H17ClN2O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1190221-43-2
Synonyms M-5441; TM 5441; BMS-790052; BMS-790052; BMS790052; EBP 883; EBP-883; EBP883
SMILES ClC1=CC=C(NC(COCC(NC2=CC=CC(C3=COC=C3)=C2)=O)=O)C(C(O)=O)=C1

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