TM5441

Catalog No.: A19369

PAI-1 inhibitor

TM5441

TM5441 Chemical Structure

CAS NO. 1190221-43-2

TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines.

Availability: In stock

Package Price Qty
2 mg
$80.00
5 mg
$130.00
10 mg
$200.00
50 mg
$720.00
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Biological Activity

TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 μM and induces intrinsic apoptosis in several human cancer cell lines.
In vitro DMSO 83 mg/mL (193.55 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.32 mL 116.6 mL 233.2 mL
0.5 mM 4.66 mL 23.32 mL 46.64 mL
1 mM 2.33 mL 11.66 mL 23.32 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 428.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19369
Actions Inhibitor
CAS No. 1190221-43-2
Formula C21H17ClN2O6
M. Wt 428.82
Purity >98%
Synonyms M-5441; TM 5441; BMS-790052; BMS-790052; BMS790052; EBP 883; EBP-883; EBP883
SMILES ClC1=CC=C(NC(COCC(NC2=CC=CC(C3=COC=C3)=C2)=O)=O)C(C(O)=O)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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