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CK2/ERK8 inhibitor

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Catalog No. A13977

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TMCB 10mg A13977-10
TMCB 25mg A13977-25
TMCB 50mg A13977-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MCB has been shown to inhibit both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8/MAPK15) (IC50 = 0.50 uM for both CK2 and ERK8).


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Chemical Information

Catalog Num A13977
Actions Inhibitor
M. Wt 534.82
Formula C11H9Br4N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 905105-89-7
Synonyms N/A
SMILES CN(C)C1=NC2=C(N1CC(=O)O)C(=C(C(=C2Br)Br)Br)Br

Biological Activity

MCB has been shown to inhibit both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8/MAPK15) (IC50 = 0.50 uM for both CK2 and ERK8).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.7 mL 93.49 mL 186.98mL
0.5 mM 3.74 mL 18.7 mL 37.4 mL
1 mM 1.87 mL 9.35 mL 18.7 mL
5 mM 0.37 mL 1.87 mL 3.74 mL

*The above data is based on the productmolecular weight 534.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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