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Biological Activity
MCB has been shown to inhibit both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8/MAPK15) (IC50 = 0.50 uM for both CK2 and ERK8).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.7 mL | 93.49 mL | 186.98 mL |
| 0.5 mM | 3.74 mL | 18.7 mL | 37.4 mL |
| 1 mM | 1.87 mL | 9.35 mL | 18.7 mL |
| 5 mM | 0.37 mL | 1.87 mL | 3.74 mL |
*The above data is based on the productmolecular weight 534.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13977 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 905105-89-7 |
| Formula | C11H9Br4N3O2 |
| M. Wt | 534.82 |
| Purity | >98% |
| SMILES | CN(C)C1=NC2=C(N1CC(=O)O)C(=C(C(=C2Br)Br)Br)Br |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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