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TMEM16A modulator-1

Catalog No.: A66536
TMEM16A Modulator
TMEM16A modulator-1 is a positive modulator of the calcium-activated chloride channel TMEM16A. This compound enhances the activity of TMEM16A, making it valuable for investigating its roles in various biological processes. It is particularly relevant for research into TMEM16A-related diseases, such as respiratory disorders, where modulation of ion channels may reveal therapeutic possibilities.
TMEM16A modulator-1 2367645-32-5 TMEM16A Modulator
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTMEM16A modulator-1 is a positive modulator of the calcium-activated chloride channel TMEM16A. This compound enhances the activity of TMEM16A, making it valuable for investigating its roles in various biological processes. It is particularly relevant for research into TMEM16A-related diseases, such as respiratory disorders, where modulation of ion channels may reveal therapeutic possibilities.
Product Information
Catalog NumA66536
FormulaC19H18ClN3O3
Molecular Weight371.82
CAS Number2367645-32-5
SMILESO=C(C1=NC=CC(NC(CC2=CC(Cl)=CC=C2O)=O)=C1)NC(C)(C)C#C
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Membrane Transporters-Ion Channels > Chloride Channels