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Publications citing Adooq Products
Chemical Information
| Catalog Num | A11138 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 388.3 |
| Formula | C26H32N2O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 851983-85-2 |
| Synonyms | VN/124-1 |
| SMILES | C[[email protected]]12CC[[email protected]@H](CC1=CC[[email protected]@H]3[[email protected]@H]2CC[[email protected]]4([[email protected]]3CC=C4N5C=NC6=CC=CC=C65)C)O |
Description |
TOK-001 (Galeterone) is both an androgen receptor antagonist and CYP17A1 inhibitor. | ||||||||||
Targets |
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| Solubility (25°C) * | In vitro | DMSO | 24 mg/mL (61.76 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 40 mg/mL (102.94 mM) | ||
| In vivo | 0.5% hydroxyethyl cellulose | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.75 mL | 128.77 mL | 257.53mL |
| 0.5 mM | 5.15 mL | 25.75 mL | 51.51 mL |
| 1 mM | 2.58 mL | 12.88 mL | 25.75 mL |
| 5 mM | 0.52 mL | 2.58 mL | 5.15 mL |
*The above data is based on the productmolecular weight 388.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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