TOK-001 (Galeterone)

Catalog No.: A11138

CYP17 inhibitor

TOK-001 (Galeterone)

TOK-001 (Galeterone) Chemical Structure

CAS NO. 851983-85-2

TOK-001 (Galeterone) is both an androgen receptor antagonist and CYP17A1 inhibitor.

Availability: In stock

Package Price Qty
5 mg
10 mg
50 mg
100 mg
10mM * 1mL in DMSO
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TOK-001 (Galeterone) is both an androgen receptor antagonist and CYP17A1 inhibitor.
CYP17 Androgen Receptor
300 nM384 nM
In vitro (25°C) DMSO 21 mg/mL (54.04 mM)
Water Insoluble
Ethanol Warmed: 36 mg/mL (92.65 mM)
In vivo 0.5% hydroxyethyl cellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.75 mL 128.77 mL 257.53 mL
0.5 mM 5.15 mL 25.75 mL 51.51 mL
1 mM 2.58 mL 12.88 mL 25.75 mL
5 mM 0.52 mL 2.58 mL 5.15 mL

*The above data is based on the productmolecular weight 388.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11138
Actions Inhibitor
CAS No. 851983-85-2
Formula C26H32N2O
M. Wt 388.3
Purity >98%
Synonyms VN/124-1
SMILES C[[email protected]]12CC[[email protected]@H](CC1=CC[[email protected]@H]3[[email protected]@H]2CC[[email protected]]4([[email protected]]3CC=C4N5C=NC6=CC=CC=C65)C)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy TOK-001 (Galeterone) | TOK-001 (Galeterone) Supplier | purchase | cost | manufacturer | order | distributor | buy 851983-85-2| 851983-85-2 Supplier | purchase 851983-85-2 | 851983-85-2 cost | 851983-85-2 manufacturer | order 851983-85-2 | 851983-85-2 distributor