Topotecan HCl (Hycamtin)

Catalog No.: A10939

DNA topoisomerase I inhibitor

Topotecan HCl (Hycamtin)

Topotecan HCl (Hycamtin) Chemical Structure

CAS NO. 119413-54-6

Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.

Availability: In stock

Package Price Qty
50 mg

Regular Price: $150.00

Special Price $120.00

100 mg

Regular Price: $250.00

Special Price $200.00

200 mg

Regular Price: $420.00

Special Price $336.00

10mM * 1mL in DMSO
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.


Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.
In vitro (25°C) DMSO 92 mg/mL (200.91 mM)
Water 92 mg/mL (200.91 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.84 mL 109.19 mL 218.39 mL
0.5 mM 4.37 mL 21.84 mL 43.68 mL
1 mM 2.18 mL 10.92 mL 21.84 mL
5 mM 0.44 mL 2.18 mL 4.37 mL

*The above data is based on the productmolecular weight 457.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10939
Actions Inhibitor
M. Wt 457.9
Formula C23H23N3O5 .HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 119413-54-6
Synonyms Hycamtin
SMILES CC[[email protected]@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl

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