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Topotecan HCl (Hycamtin)

Catalog No.: A10939

DNA topoisomerase I inhibitor

Topotecan HCl (Hycamtin)

Topotecan HCl (Hycamtin) Chemical Structure

CAS NO. 119413-54-6

Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.

Availability: In stock

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50 mg
100 mg
200 mg
10mM * 1mL in DMSO
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.
In vitro (25°C) DMSO 87 mg/mL (189.99 mM)
Water 87 mg/mL (189.99 mM)
Ethanol Insoluble
In vivo Saline 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.84 mL 109.19 mL 218.39 mL
0.5 mM 4.37 mL 21.84 mL 43.68 mL
1 mM 2.18 mL 10.92 mL 21.84 mL
5 mM 0.44 mL 2.18 mL 4.37 mL

*The above data is based on the productmolecular weight 457.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10939
Actions Inhibitor
CAS No. 119413-54-6
Formula C23H23N3O5 .HCl
M. Wt 457.9
Purity >98%
Synonyms Hycamtin
SMILES CC[[email protected]@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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