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Biological Activity
Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.
| In vitro (25°C) | DMSO | 87 mg/mL (189.99 mM) | |
| Water | 87 mg/mL (189.99 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | Saline | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.84 mL | 109.19 mL | 218.39 mL |
| 0.5 mM | 4.37 mL | 21.84 mL | 43.68 mL |
| 1 mM | 2.18 mL | 10.92 mL | 21.84 mL |
| 5 mM | 0.44 mL | 2.18 mL | 4.37 mL |
*The above data is based on the productmolecular weight 457.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10939 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 119413-54-6 |
| Formula | C23H23N3O5 .HCl |
| M. Wt | 457.9 |
| Purity | >98% |
| Synonyms | Hycamtin |
| SMILES | CC[[email protected]@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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