Biological Activity
Topotecan is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
In vitro | DMSO | 76 mg/mL (180.33 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.73 mL | 118.64 mL | 237.28 mL |
0.5 mM | 4.75 mL | 23.73 mL | 47.46 mL |
1 mM | 2.37 mL | 11.86 mL | 23.73 mL |
5 mM | 0.47 mL | 2.37 mL | 4.75 mL |
*The above data is based on the productmolecular weight 421.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16815 |
---|---|
Actions | Inhibitor |
CAS No. | 123948-87-8 |
Formula | C23H23N3O5 |
M. Wt | 421.45 |
Purity | >98% |
Synonyms | SKF104864, SKF 104864, SKF-104864, NSC 609669, NSC609669, NSC-609669 |
SMILES | O=C1[[email protected]](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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