Tos-PEG3-CH2COOtBu is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the formation of bifunctional molecules that can selectively induce the degradation of target proteins via the ubiquitin-proteasome pathway. Its application is critical in chemical biology for the development of targeted protein degradation strategies and probing protein function in various cellular contexts.
Tos-PEG3-CH2COOtBu is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the formation of bifunctional molecules that can selectively induce the degradation of target proteins via the ubiquitin-proteasome pathway. Its application is critical in chemical biology for the development of targeted protein degradation strategies and probing protein function in various cellular contexts.
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