TP-16

Catalog No.: A63239
EP4 Antagonist
TP-16 is a selective antagonist of the EP4 receptor, demonstrating an IC50 value of 2.1 nM. This compound effectively inhibits EP4-mediated signaling pathways, making it a valuable tool for investigating the role of EP4 in various physiological and pathological processes. TP-16 is particularly relevant for research in inflammation, pain, and cancer biology, providing insights into therapeutic interventions targeting the prostaglandin receptor system.
Grouped product items
Size Price Stock Qty
1mg
$220.00
In stock
2mg
$325.00
In stock
5mg
$525.00
In stock
10mg
$725.00
In stock
25mg
$1,065.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTP-16 is a selective antagonist of the EP4 receptor, demonstrating an IC50 value of 2.1 nM. This compound effectively inhibits EP4-mediated signaling pathways, making it a valuable tool for investigating the role of EP4 in various physiological and pathological processes. TP-16 is particularly relevant for research in inflammation, pain, and cancer biology, providing insights into therapeutic interventions targeting the prostaglandin receptor system.
Product Information
Catalog NumA63239
FormulaC24H22FNO4S
Molecular Weight439.50
CAS Number2332972-26-4
SMILESC[C@@H](C1=CC=C(C=C1)C(O)=O)NC(C2=C(CC3=CC=C(C=C3)F)SC4=C2CCOC4)=O
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