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TP508

Catalog No.: A65347
Thrombin Peptide
TP508 is a 23-amino acid nonproteolytic thrombin peptide that selectively targets the receptor-binding domain of thrombin. It activates endothelial nitric oxide synthase (eNOS) and promotes nitric oxide production in human endothelial cells, facilitating enhanced endothelial cell activation and stem cell recruitment. This molecule is of significant interest for applications in tissue revascularization and regenerative medicine research.
TP508 121341-81-9 Thrombin Peptide
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Size Price Stock Qty
1mg
$95.00
In stock
5mg
$385.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTP508 is a 23-amino acid nonproteolytic thrombin peptide that selectively targets the receptor-binding domain of thrombin. It activates endothelial nitric oxide synthase (eNOS) and promotes nitric oxide production in human endothelial cells, facilitating enhanced endothelial cell activation and stem cell recruitment. This molecule is of significant interest for applications in tissue revascularization and regenerative medicine research.
Product Information
Catalog NumA65347
FormulaC97H146N28O36S
Molecular Weight2312.44
CAS Number121341-81-9
SequenceAla-Gly-Tyr-Lys-Pro-Asp-Glu-Gly-Lys-Arg-Gly-Asp-Ala-Cys-Glu-Gly-Asp-Ser-Gly-Gly-Pro-Phe-Val
Sequence shorteningAGYKPDEGKRGDACEGDSGGPFV
SMILESC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC(CNC([C@H](C)N)=O)=O)=O)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(NCC(=O)N3[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](C(C)C)C(O)=O)=O)=O)CCC3)=O)=O)CO)=O)CC(O)=O)=O)=O)CCC(O)=O)=O)CS)=O)C)=O)CC(O)=O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)CCC2
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Proteases > Thrombin
Peptides