trans-4-Cyanocyclohexane-1-carboxylic acid

Catalog No.: A82239
PROTAC Linker
trans-4-Cyanocyclohexane-1-carboxylic acid serves as a versatile linker in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins to E3 ligases, enabling targeted protein degradation. Its unique structure enhances hydrophilicity and may improve cellular permeability, making it suitable for various applications in drug discovery and the study of protein function and regulation.
Grouped product items
Size Price Stock Qty
100mg
$20.00
In stock
250mg
$35.00
In stock
500mg
$55.00
In stock
1g
$100.00
In stock
5g
$345.00
In stock
10g
$540.00
In stock
25g
$1,160.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiontrans-4-Cyanocyclohexane-1-carboxylic acid serves as a versatile linker in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins to E3 ligases, enabling targeted protein degradation. Its unique structure enhances hydrophilicity and may improve cellular permeability, making it suitable for various applications in drug discovery and the study of protein function and regulation.
Product Information
Catalog NumA82239
FormulaC8H11NO2
Molecular Weight153.18
CAS Number15177-68-1
SMILESC(O)(=O)[C@H]1CC[C@H](C#N)CC1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2