trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc serves as a PROTAC linker, facilitating targeted protein degradation through the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the synthesis of PROTAC SMARCA2/4-degrader-35, enhancing the selective degradation of specific proteins associated with various cellular processes. Its application in research enables the exploration of protein functions and therapeutic strategies in the field of targeted protein modulation.
trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc serves as a PROTAC linker, facilitating targeted protein degradation through the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the synthesis of PROTAC SMARCA2/4-degrader-35, enhancing the selective degradation of specific proteins associated with various cellular processes. Its application in research enables the exploration of protein functions and therapeutic strategies in the field of targeted protein modulation.
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