Trequinsin hydrochloride is a highly potent inhibitor of platelet cyclic adenosine monophosphate (cAMP) phosphodiesterase (PDE), exhibiting an IC50 value of 0.25 nM. This compound effectively prevents the aggregation of human platelets induced by various agonists, including ADP, collagen, thrombin, and epinephrine. Trequinsin hydrochloride serves as a valuable tool for research applications focused on platelet function and the modulation of vascular responses.
Trequinsin hydrochloride is a highly potent inhibitor of platelet cyclic adenosine monophosphate (cAMP) phosphodiesterase (PDE), exhibiting an IC50 value of 0.25 nM. This compound effectively prevents the aggregation of human platelets induced by various agonists, including ADP, collagen, thrombin, and epinephrine. Trequinsin hydrochloride serves as a valuable tool for research applications focused on platelet function and the modulation of vascular responses.
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