Trimethadione

Catalog No.: A17688

Trimethadione

Trimethadione Chemical Structure

CAS NO. 127-48-0

Trimethadione is an oxazolidinedione anticonvulsant. It is most commonly used to treat epileptic conditions that are resistant to other treatments. Trimethadione (TMO) has the properties required of probe drugs for the evaluation of hepatic drug-oxidizing capacity in humans in vivo.

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50 mg

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Warning WARNING: Attention California Residents: This product can expose you to chemicals including Trimethadione , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Trimethadione is an oxazolidinedione anticonvulsant. It is most commonly used to treat epileptic conditions that are resistant to other treatments. Trimethadione (TMO) has the properties required of probe drugs for the evaluation of hepatic drug-oxidizing capacity in humans in vivo.
In vitro DMSO 26 mg/mL (181.64 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 69.86 mL 349.31 mL 698.62 mL
0.5 mM 13.97 mL 69.86 mL 139.72 mL
1 mM 6.99 mL 34.93 mL 69.86 mL
5 mM 1.4 mL 6.99 mL 13.97 mL

*The above data is based on the productmolecular weight 143.14. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17688
CAS No. 127-48-0
Formula C6H9NO3
M. Wt 143.14
Purity >98%
Synonyms Tridione; Trimethadione; Trimetin; Troxidone.
SMILES O=C(N1C)OC(C)(C)C1=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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