Troxacitabine triphosphate

Catalog No.: A56489
DNA Polymerases Substrate
Troxacitabine triphosphate (TRX-TP) serves as a substrate for DNA polymerases, specifically targeting replicative and repair enzymes. This compound demonstrates key biological activity by facilitating DNA synthesis and repair processes in vitro. It is valuable for research applications that involve the study of nucleotide incorporation and polymerase activity, providing insights into DNA replication and repair mechanisms.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTroxacitabine triphosphate (TRX-TP) serves as a substrate for DNA polymerases, specifically targeting replicative and repair enzymes. This compound demonstrates key biological activity by facilitating DNA synthesis and repair processes in vitro. It is valuable for research applications that involve the study of nucleotide incorporation and polymerase activity, providing insights into DNA replication and repair mechanisms.
Product Information
Catalog NumA56489
FormulaC8H14N3O13P3
Molecular Weight453.13
CAS Number171039-00-2
SMILESO=C1N([C@H]2O[C@H](OC2)COP(OP(OP(O)(O)=O)(O)=O)(O)=O)C=CC(N)=N1
SynonymsTRX-TP
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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