TRPV1 agonist-1 is a potent agonist of the transient receptor potential vanilloid 1 (TRPV1) channel, exhibiting EC50 values of 4.5 nM and 0.57 nM for human and rat TRPV1, respectively. This compound is effective in enhancing swallowing function in preclinical rat models, making it valuable for investigating dysphagia and related disorders. Its non-irritating profile allows for potential applications in functional studies involving TRPV1 modulation.
TRPV1 agonist-1 is a potent agonist of the transient receptor potential vanilloid 1 (TRPV1) channel, exhibiting EC50 values of 4.5 nM and 0.57 nM for human and rat TRPV1, respectively. This compound is effective in enhancing swallowing function in preclinical rat models, making it valuable for investigating dysphagia and related disorders. Its non-irritating profile allows for potential applications in functional studies involving TRPV1 modulation.
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