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TRPV1-IN-3

Name: TRPV1-IN-3
Brand: Adooq Bioscience
SKU: A68806
Availability: OutOfStock

Cat. No. A68806 CAS 87657-67-8

TRPV1 Inhibitor

TRPV1-IN-3 is a selective inhibitor of the transient receptor potential vanilloid 1 (TRPV1) channel, demonstrating significant antifibrotic activity in vitro with an IC50 of 0.51 μM. Its mechanism involves the modulation of fibrosis markers such as collagen I and α-SMA through inhibition of the TGF-β/Smads and MAPK signaling pathways. Research applications include studying idiopathic pulmonary fibrosis, where TRPV1-IN-3 has been shown to reduce collagen deposition in lung tissue, enhance alveolar structure, and increase survival rates in Bleomycin-induced pulmonary fibrosis models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	87657-67-8
Applications	TRPV1 Inhibitor
Formula	C₁₉H₂₀O₃
Molecular Weight	296.36
SMILES	O=C(CCCCC1=CC=CC=C1)/C=C/C2=CC(O)=C(C=C2)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.