TTC-352 is an orally bioavailable selective partial agonist of the human estrogen receptor (ER) α, classified as a ShERPA. It effectively inhibits the proliferation of estrogen receptor-positive breast cancer cells, demonstrating significant antitumor activity. Additionally, TTC-352 promotes tumor regression by facilitating the translocation of ERα from the nucleus to extranuclear locations, making it a valuable tool for research in breast cancer therapeutics.
TTC-352 is an orally bioavailable selective partial agonist of the human estrogen receptor (ER) α, classified as a ShERPA. It effectively inhibits the proliferation of estrogen receptor-positive breast cancer cells, demonstrating significant antitumor activity. Additionally, TTC-352 promotes tumor regression by facilitating the translocation of ERα from the nucleus to extranuclear locations, making it a valuable tool for research in breast cancer therapeutics.
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