Tubulin inhibitor 49

Catalog No.: A54965
Tubulin Inhibitor
Tubulin Inhibitor 49 is a potent tubulin polymerization inhibitor with an IC50 value of 48 μM. This compound disrupts the microtubule network, leading to G2 phase cell cycle arrest and demonstrating cytotoxicity with an IC50 of 8.8 μM in HeLa cells. Tubulin Inhibitor 49 serves as a valuable tool for researching cervical cancer and understanding the mechanisms of microtubule dynamics in cancer cell proliferation.
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
5mg
$90.00
In stock
10mg
$150.00
In stock
25mg
$300.00
In stock
50mg
$465.00
In stock
100mg
$715.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTubulin Inhibitor 49 is a potent tubulin polymerization inhibitor with an IC50 value of 48 μM. This compound disrupts the microtubule network, leading to G2 phase cell cycle arrest and demonstrating cytotoxicity with an IC50 of 8.8 μM in HeLa cells. Tubulin Inhibitor 49 serves as a valuable tool for researching cervical cancer and understanding the mechanisms of microtubule dynamics in cancer cell proliferation.
Product Information
Catalog NumA54965
FormulaC18H14F3N3OS
Molecular Weight377.38
CAS Number1023875-75-3
SMILESO=C(C)NC1=CC=C(C2=CSC(NC3=CC=CC(C(F)(F)F)=C3)=N2)C=C1
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