Tubulin polymerization-IN-30 is an effective inhibitor of tubulin polymerization, specifically targeting the colchicine binding site. By disrupting microtubule organization, it induces cell cycle arrest at the G2/M phase. This compound demonstrates significant antiproliferative activity against various cancer cell lines, including SGC-7901, A549, and HeLa, with respective IC50 values of 2.16, 2.21, and 0.403 μM, making it a valuable tool for cancer research applications.
Tubulin polymerization-IN-30 is an effective inhibitor of tubulin polymerization, specifically targeting the colchicine binding site. By disrupting microtubule organization, it induces cell cycle arrest at the G2/M phase. This compound demonstrates significant antiproliferative activity against various cancer cell lines, including SGC-7901, A549, and HeLa, with respective IC50 values of 2.16, 2.21, and 0.403 μM, making it a valuable tool for cancer research applications.
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