Tubulin polymerization-IN-4 is a potent inhibitor of tubulin polymerization, exhibiting an IC50 value of 4.6 μM. This compound effectively disrupts tubulin dynamics, leading to cell cycle arrest at the G2/M phase, induction of apoptosis, and inhibition of both clonogenesis and migration in HeLa cells. Tubulin polymerization-IN-4 serves as a valuable tool in research related to cervical cancer, facilitating the exploration of therapeutic strategies targeting tubulin dynamics.
Tubulin polymerization-IN-4 is a potent inhibitor of tubulin polymerization, exhibiting an IC50 value of 4.6 μM. This compound effectively disrupts tubulin dynamics, leading to cell cycle arrest at the G2/M phase, induction of apoptosis, and inhibition of both clonogenesis and migration in HeLa cells. Tubulin polymerization-IN-4 serves as a valuable tool in research related to cervical cancer, facilitating the exploration of therapeutic strategies targeting tubulin dynamics.
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