Tubulysin B is a potent microtubule destabilizing agent that selectively inhibits tubulin polymerization. Naturally derived from the myxobacteria Archangium geophyra and Angiococcus disciformis, it exhibits high cytotoxicity with IC50 values in the picomolar range across various cancer cell lines, including those exhibiting multidrug resistance. This compound is valuable for studies focused on cancer biology, specifically in elucidating mechanisms of cell cycle arrest and apoptosis.
Tubulysin B is a potent microtubule destabilizing agent that selectively inhibits tubulin polymerization. Naturally derived from the myxobacteria Archangium geophyra and Angiococcus disciformis, it exhibits high cytotoxicity with IC50 values in the picomolar range across various cancer cell lines, including those exhibiting multidrug resistance. This compound is valuable for studies focused on cancer biology, specifically in elucidating mechanisms of cell cycle arrest and apoptosis.
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