Tubulysin C is a potent anti-microtubule toxin that targets tubulin, effectively disrupting microtubule dynamics. This compound exhibits significant cytotoxic activity in mammalian cells, including those resistant to multiple drugs, with IC50 values in the low nanomolar range. Tubulysin C inhibits microtubule polymerization, resulting in cell cycle arrest and apoptosis. It is valuable for research in cancer biology and the development of targeted therapies.
Tubulysin C is a potent anti-microtubule toxin that targets tubulin, effectively disrupting microtubule dynamics. This compound exhibits significant cytotoxic activity in mammalian cells, including those resistant to multiple drugs, with IC50 values in the low nanomolar range. Tubulysin C inhibits microtubule polymerization, resulting in cell cycle arrest and apoptosis. It is valuable for research in cancer biology and the development of targeted therapies.
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